Endocrine Abstracts

While increasing levels of thyroxine may be a risk factor for venous thromboembolism (van Zaane et al. Blood 2010 115(22) 4344–4349), there is a relative lack of detailed data on the effect of thyroid hormones on haemostatic system. We analyzed multiple markers of haemostasis in a cohort of patients shifting from severe hypothyroidism to mild hyperthyroidism during their differentiated thyroid cancer treatment.In 94 patients fol...

On their first antenatal visit (median 10th gestational week), 977 pregnant women in one district were assayed for TSH (IRMA, non-pregnant normal range 0,15-5 mIU/l) and TPO-Ab (RIA). Abnormal values were found in 154 women (15.8%): positive TPO-Ab in 92 (9.4%), TSH<0,15 in 35 (3.6%), TSH>5 in 49 (5.0%). Of them, 128 women were examined in our endocrine clinic (median 15th week), incl. thyroid ultrasonography (7.5 MHz, Doppler), and assayed for TSH, free T4, free T3, a...

Objective: Numerous abnormalities of thyroid hormones in end-stage renal disease (ESRD) have been described. Our aim was to analyze the impact of these abnormalities on survival.Design: In 167 haemodialyzed ESRD patients, TSH and thyroid hormone levels (including reverse T3, i.e. T4, fT4, T3, fT3, rT3) were determined. The patients were then prospectively followed up for up to 5 years and ...